杨启文，研究员，博士生导师，北京协和医学院医学博士。国家“万人计划”科技创新领军人才，欧洲临床微生物和感染病学会华人药敏委员会（ChiCAST）主席、国家卫生健康委临床抗微生物药物敏感性折点研究和标准制定专家委员会副主任委员。以第一完成人获北京市科技进步奖二等奖、麒麟科学技术奖-科技创新奖，并荣获多项其他省部级科技奖励。主持国家科技重大专项、国家重点研发计划、国家自然科学基金等多项国家级重大科研项目。其系统性的研究与实践工作，显著提升了我国感染性疾病的精准诊疗与防控水平。

长期致力于临床重要致病菌的耐药机制、分子流行病学及新型病原诊断技术研究。构建了包含全国多中心监测、耐药机制研究、新药评价、快速诊断研发及检测标准化在内的五大创新平台体系。牵头组建我国首个药敏折点国际组织ChiCAST，设立自主知识产权药敏折点，填补行业空白。以第一/通讯作者在《Lancet Microbe》等期刊发表SCI论文80余篇，累计影响因子达534.9。授权国内外发明专利40项，成功研发并转化多项快速检测技术，产品销售额超亿元，广泛应用于临床，为遏制细菌耐药作出突出贡献。

中国足球彩票

1.Zhu Y#, Miao H#, Zhang J#, Jiang Z#, Chu X#, Xu Y, Tian W, Gao H, Zhu Y, Li L*, Yang Q*(corresponding author). Role of plasma and blood-cell co-metagenomic sequencing in precise diagnosis and severity evaluation of sepsis, a prospective cohort study in sepsis patients. J Infect. 2025 Jan 31:106434.（IF=14.3）

2.Jia X#, Zhu Y#, Jia P, Li C, Chu X#, Sun T, Liu X, Yu W, Chen F, Xu Y, Yang Q*(corresponding author). The key role of iroBCDN-lacking pLVPK-like plasmid in the evolution of the most prevalent hypervirulent carbapenem-resistant ST11-KL64 Klebsiella pneumoniae in China. Drug Resist Updat. 2024;77:101137.（IF=15.8）

3.Zhu Y#, Jia P, Yu W, Chu X, Liu X, Yang Q*(corresponding author). The epidemiology and virulence of carbapenem-resistant Pseudomonas aeruginosa in China. Lancet Microbe. 2023 Jun 13:S2666-5247(23)00113-1. （IF=86.21）

4.Yang XZ#, Sun TS#, Jia PY#, Li SJ#, Li XG, Shi Y, Li X, Gao H, Yin H, Jia XM*, Yang Q*(corresponding author). A-to-I RNA Editing in Klebsiella pneumoniae Regulates Quorum Sensing and Affects Cell Growth and Virulence. Adv Sci (Weinh). 2023 Apr 21:e2206056.（IF=17.52）

5.Yu W#, Zhang H#, Zhu Y, Jia P, Xu Y*, Yang Q*(corresponding author). In vitro activity of ceftolozane/tazobactam against Pseudomonas aeruginosa collected in the Study for Monitoring Antimicrobial Resistance Trends (SMART) between 2016-2019 in China. Int J Antimicrob Agents. 2023 Feb 1:106741. （IF=15.44）

6.Zhang D#, Zhang J#, Du J#, Zhou Y#, Wu P, Liu Z, Sun Z, Wang J, Ding W, Chen J, Wang J, Xu Y, Ouyang C*, Yang Q*(corresponding author). Optimized Sequencing Adaptors Enable Rapid and Real-Time Metagenomic Identification of Pathogens during Runtime of Sequencing. Clin Chem. 2022;68(6):826-836.. (IF=8.327)

7.Liu X#, Wu Y#, Zhu Y#, Jia P, Li X, Jia X, Yu W, Cui Y, Yang R, Xia W*, Xu Y*, Yang Q*(corresponding author). Emergence of colistin-resistant hypervirulent Klebsiella pneumoniae (CoR-HvKp) in China. Emerg Microbes Infect. 2022, 11(1):648-661.(IF=19.568)

8.Jia X#, Li C#, Chen F#, Li X#, Jia P#, Zhu Y#, Sun T, Hu F, Jiang X, Yu Y, Hu B, Yang Q, Kang M, Liang H, Liao K, Hu L, Gu L, Jin Y, Duan Q, Zhang S, Sun Z, Huang W, He H, Shao H, Shan B, Zhuo C, Ji P, Zheng R, Li G, Xu Y, Yang Q*(corresponding author). Genomic epidemiology study of Klebsiella pneumoniae causing bloodstream infections in China. Clin Transl Med. 2021 Nov;11(11):e624. (IF=11.492)

9.Yang Q#, Zhang H#, Yu Y, Kong H, Duan Q, Wang Y, Zhang S, Sun Z, Liao K, Gu L, Jiang X, Wu A, Huang W, Shan B, Kang M, Hu F, Yu H, Zhang W, Xu Y*. In Vitro Activity of Imipenem/Relebactam Against Enterobacteriaceae Isolates Obtained from Intraabdominal, Respiratory Tract, and Urinary Tract Infections in China: Study for Monitoring Antimicrobial Resistance Trends (SMART), 2015-2018. Clin Infect Dis. 2020, 71(S4): S427-435. (IF=8.313)

10.Yang Q#*(corresponding author), Jia X#, Zhou M#, Zhang H, Yang W, Kudinha T, Xu Y*. Emergence of ST11-K47 and ST11-K64 hypervirulent carbapenem- resistant Klebsiella pneumoniae in bacterial liver abscesses from China: a molecular, biological, and epidemiological study. Emerg Microbes Infect. 2020, 9(1):320-331. (IF=5.776)